Tudorza Pressair is a brand-name prescription drug inhaler that’s used to treat chronic obstructive pulmonary disease (COPD) in adults. COPD is a condition that includes several lung diseases that get worse over time, such as emphysema and chronic bronchitis. With COPD, you may have shortness of breath, coughing, or wheezing.

Tudorza Pressair contains the active drug aclidinium, which belongs to a class of drugs called anticholinergics. Tudorza treats COPD by relaxing the muscles in your airways. This helps open your airways, making it easier to breathe.

Pressair is the inhaler that’s used to breathe in the Tudorza medication. The drug comes as a dry powder that’s inhaled through the mouth and into the lungs. It comes in a dose of 400 micrograms (mcg) per puff.

Effectiveness

In three clinical studies, Tudorza Pressair was evaluated in adults with COPD over a period of 3 to 6 months. People took either Tudorza Pressair or a placebo (a treatment with no active drug) twice daily.

Tudorza was compared to a placebo using a value called forced expiratory volume in 1 second (FEV1). This measures how much air you can force from your lungs in 1 second. A “normal” FEV1 is different for each person. But a higher FEV1 indicates better lung function than a lower FEV1.

FEV1 was measured in the beginning of the clinical studies and again at 12 weeks. People who used Tudorza Pressair saw an average improvement in FEV1 of 0.06 L to 0.10 L over the course of the study. In comparison, those who took a placebo saw an average decrease in their FEV1 of 0.01 L to 0.05 L.

Tudorza Pressair is available only as a brand-name medication. It’s not currently available in generic form. A generic drug is an exact copy of a brand-name medication. Generics tend to cost less than brand-name drugs.

Tudorza Pressair contains the active drug aclidinium, which belongs to a class of drugs called anticholinergics.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Drug forms and strengths

Tudorza Pressair comes as a powder that’s inhaled through the mouth and into the lungs. It comes in a dose of 400 mcg per puff.

Dosage for chronic obstructive pulmonary disease (COPD)

You should take one puff of Tudorza Pressair twice a day, about 12 hours apart.

What if I miss a dose?

If you miss a dose of Tudorza Pressair, just skip the missed dose. Then take the next dose at your regularly scheduled time. Never take an extra dose to make up for a missed dose. This can raise your risk of side effects.

To help make sure you don’t miss a dose, try setting a reminder on your phone. A medication timer may be useful, too.

Will I need to use this drug long term?

Tudorza Pressair is meant to be used as a long-term treatment because COPD is a lifelong disease that gets worse over time. If you and your doctor determine that Tudorza Pressair is safe and effective for you, you’ll likely take it long term.

Tudorza Pressair can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking Tudorza Pressair. These lists do not include all possible side effects.

For more information on the possible side effects of Tudorza Pressair, talk with your doctor or pharmacist. They can give you tips on how to deal with any side effects that may be bothersome.

Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. If you would like to report to the FDA a side effect you’ve had with Tudorza Pressair, you can do so through MedWatch.

Mild side effects

The more common* mild side effects of Tudorza Pressair can include:

  • headache
  • common cold symptoms like a stuffy or runny nose
  • cough

The less common** mild side effects of Tudorza Pressair can include:

  • diarrhea
  • toothache
  • falling
  • vomiting
  • sinus infection

* Occurred in more than 3% of people in clinical studies

** Occurred in less than 3% of people in clinical studies

Most of these side effects may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk with your doctor or pharmacist.

Serious side effects

Serious side effects from Tudorza Pressair aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life threatening or if you think you’re having a medical emergency.

Serious side effects and their symptoms can include:

  • Bronchospasm (tightening of the airways). Symptoms can include:
    • difficulty breathing
    • coughing
  • New or worsening narrow-angle glaucoma (increased pressure in the eyes). Symptoms can include:
    • eye pain that comes on suddenly
    • blurry vision
    • seeing “halos” or bright colors around lights
    • whites of the eyes turning red
  • New or worsening urinary retention (not being able to completely empty your bladder). Symptoms can include:
    • painful urination
    • trouble passing urine
    • urinating often
    • urinating in a weak stream or in drips

Other serious side effects are explained in more detail below in. These include:

Side effect details

You may wonder how often certain side effects occur with this drug. Here’s some detail on several of the side effects this drug may cause.

Allergic reaction

As with most drugs, some people can have an allergic reaction after taking Tudorza Pressair. Symptoms of a mild allergic reaction can include:

  • skin rash
  • itchiness
  • flushing (warmth and redness in your skin)

A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:

  • swelling under your skin, typically in your eyelids, lips, hands, or feet
  • swelling of your tongue, mouth, or throat
  • trouble breathing

Call your doctor right away if you have a severe allergic reaction to Tudorza Pressair. Call 911 if your symptoms feel life threatening or if you think you’re having a medical emergency.

High blood pressure

High blood pressure may be a rare side effect that happens when taking Tudorza Pressair.

A 3-year clinical study evaluated Tudorza Pressair’s safety for heart health in people who have COPD and a higher risk of experiencing a cardiovascular-related event like a heart attack or stroke. In this study, most of the people had a history of heart disease or stroke, or they had other heart-related risk factors.

Tudorza Pressair was shown to be as safe for heart health as a placebo (a treatment with no active drug). However, at least 2% of the people in the study experienced high blood pressure as a possible side effect of Tudorza.

Headache

Some people may get a headache while taking Tudorza Pressair. In clinical studies, 6.6% of people who took Tudorza Pressair experienced a headache. In comparison, 5% of people who took a placebo experienced a headache.

Common cold

The common cold, or symptoms that feel like the common cold, are a possible side effect of Tudorza Pressair. In clinical studies, 5.5% of people who took Tudorza Pressair experienced the common cold, compared with 3.9% of people who took a placebo.

In this clinical study, swollen sinuses and stuffy nose were also seen. Of the people who took Tudorza Pressair, 1.7% experienced swollen sinuses, and 1.6% had a stuffy nose. In comparison, 0.8% of people who took a placebo experienced swollen sinuses, and 1.2% had a stuffy nose.

Other drugs are available that can treat chronic obstructive pulmonary disease (COPD). Some may be a better fit for you than others. If you’re interested in finding an alternative to Tudorza Pressair, talk with your doctor. They can tell you about other medications that may work well for you.

Note: Some of the drugs listed here are used off-label to treat these specific conditions. Off-label use is when a drug that’s approved to treat one condition is used to treat a different condition.

Alternatives for COPD

Examples of other drugs that may be used to treat COPD include:

You may wonder how Tudorza Pressair compares with other medications that are prescribed for similar uses. Here we look at how Tudorza Pressair and Spiriva are alike and different.

Ingredients

Tudorza Pressair contains the active drug aclidinium bromide. Spiriva contains the active drug tiotropium bromide. They both contain active drugs that belong to a class called anticholinergics.

Uses

Both Tudorza Pressair and Spiriva are both FDA-approved to treat chronic obstructive pulmonary disease (COPD) in adults.

One form of Spiriva (Spiriva Respimat) is also FDA-approved to treat asthma in adults and in children ages 6 years old or older.

Drug forms and administration

Tudorza Pressair comes as a powder that’s inhaled through the mouth and into the lungs. It’s taken as one puff, twice a day. The doses should be taken about 12 hours apart.

Spiriva is available in two forms. The Spiriva HandiHaler comes as a capsule with powder in it that’s inhaled through the mouth and into the lungs. It’s taken as two puffs, once a day.

Spiriva Respimat comes as an inhaler that contains a liquid that’s inhaled through the mouth and into the lungs. For COPD, Spiriva Respimat should be taken as two puffs, once a day.

Side effects and risks

Tudorza Pressair and Spiriva have some similar side effects and others that differ. Below are examples of these side effects.

Mild side effects

These lists contain examples of mild side effects that can occur with Tudorza Pressair, with Spiriva, or with both drugs (when taken individually).

  • Can occur with Tudorza Pressair:
    • headache
    • cough
    • diarrhea
    • toothache
    • falling
    • vomiting
  • Can occur with Spiriva:
    • sore throat
    • general chest pain
    • urinary tract infection
    • indigestion (upset stomach)
    • constipation
    • increased heart rate
    • blurred vision
  • Can occur with both Tudorza Pressair and Spiriva:

Serious side effects

This list contains examples of serious side effects that can occur with both Tudorza Pressair and Spiriva (when taken individually).

  • bronchospasm (tightening of the airways)
  • new or worsening narrow-angle glaucoma (increased pressure in the eyes)
  • new or worsening urinary retention (not being able to completely empty your bladder)
  • allergic reaction

Effectiveness

Tudorza Pressair and Spiriva have different FDA-approved uses, but they’re both used to treat COPD in adults.

The use of Tudorza Pressair and Spiriva in treating COPD has been directly compared in a 6-week clinical study. Adults with COPD were given either Tudorza Pressair or Spiriva.

To see how well each drug improved breathing, a value called forced expiratory volume in 1 second (FEV1) was used. This measures how much air you can force from your lungs in 1 second. A “normal” FEV1 is different for each person. But a higher FEV1 indicates better lung function than a lower FEV1.

At the end of the 6 weeks, people who used Tudorza and Spiriva saw similar improvements in their FEV1. People who used Tudorza also saw a decrease in their COPD symptoms, including early morning coughing, wheezing, shortness of breath, and phlegm.

Costs

Tudorza Pressair and Spiriva are both brand-name drugs. There are currently no generic forms of either drug. Brand-name medications usually cost more than generics.

Tudorza Pressair generally costs less than Spiriva. The actual price you’ll pay for either drug depends on your insurance plan, your location, and the pharmacy you use.

Like Spiriva (above), the drug Anoro Ellipta has uses similar to those of Tudorza Pressair. Here’s a comparison of how Tudorza Pressair and Anoro Ellipta are alike and different.

Ingredients

Tudorza Pressair contains the active drug aclidinium bromide. Anoro Ellipta contains the active drugs umeclidinium bromide and vilanterol trifenatate powder. They both contain active drugs that belong to a drug class called anticholinergics. Anoro Ellipta also contains a long-acting beta2-agonist (LABA).

Uses

Both Tudorza Pressair and Anoro Ellipta are FDA-approved to treat chronic obstructive pulmonary disease (COPD) in adults.

Drug forms and administration

Tudorza Pressair comes as a powder that’s inhaled through the mouth and into the lungs. It’s taken as one puff, twice a day. The doses should be taken about 12 hours apart.

Anoro Ellipta also comes as a powder that’s inhaled through the mouth and into the lungs. It’s taken as one puff, once a day. Anoro Ellipta should be taken at the same time every day.

Side effects and risks

Tudorza Pressair and Anoro Ellipta have some similar side effects and other that vary. Below are examples of these side effects.

Mild side effects

These lists contain examples of mild side effects that can occur with Tudorza Pressair, with Anoro Ellipta, or with both drugs (when taken individually).

  • Can occur with Tudorza Pressair:
    • headache
    • cough
    • toothache
    • falling
    • vomiting
  • Can occur with Anoro Ellipta:
  • Can occur with both Tudorza Pressair and Anoro Ellipta:
    • diarrhea

Serious side effects

These lists contain examples of serious side effects that can occur with Anoro Ellipta or with both drugs (when taken individually).

  • Can occur with Anoro Ellipta:
    • increased blood pressure
    • fast or irregular heart beat
    • tremor
    • nervousness
    • high blood sugar level
    • hypokalemia (low potassium levels), which can lead to muscle pain and heart problems
  • Can occur with both Tudorza Pressair and Anoro Ellipta:
    • new or worsening narrow-angle glaucoma (increased pressure in the eyes)
    • allergic reaction

Effectiveness

The only condition both Tudorza Pressair and Anoro Ellipta are used to treat is chronic obstructive pulmonary disease (COPD).

These drugs haven’t been directly compared in clinical studies. However, studies have found both Tudorza Pressair and Anoro Ellipta to be effective for treating COPD.

Costs

Tudorza Pressair and Anoro Ellipta are both brand-name drugs. There are currently no generic forms of either drug. Brand-name medications usually cost more than generics.

Tudorza Pressair generally costs less than Anoro Ellipta. The actual price you’ll pay for either drug depends on your insurance plan, your location, and the pharmacy you use.

You should take Tudorza Pressair according to your doctor’s or healthcare provider’s instructions. Tudorza Pressair comes as a powder that’s inhaled through the mouth and into the lungs. It comes in a dose of 400 mcg for each puff.

When to take

You should take Tudorza Pressair as one puff, twice a day. The doses should be taken about 12 hours apart.

To help make sure you don’t miss a dose, try setting a reminder in your phone. A medication timer may be useful, too.

The Food and Drug Administration (FDA) approves prescription drugs such as Tudorza Pressair to treat certain conditions. Tudorza Pressair may also be used off-label for other conditions. Off-label use is when a drug that’s approved to treat one condition is used to treat a different condition.

Tudorza Pressair for chronic obstructive pulmonary disease (COPD)

Tudorza Pressair is a brand-name prescription drug inhaler that’s used to treat COPD in adults. COPD is a condition that includes several lung diseases that get worse over time, such as emphysema and chronic bronchitis. With COPD, you may have shortness of breath, coughing, or wheezing.

Pressair is the inhaler that’s used to breathe in the active drug in Tudorza (aclidinium), which belongs to a drug class called anticholinergics. Tudorza treats COPD by relaxing the muscles in your airways. This helps open your airways, making it easier to breathe.

You’ll use Tudorza Pressair twice a day (about 12 hours apart) to control your COPD over time. Tudorza Pressair is not a rescue inhaler, and you shouldn’t use it when you have having sudden breathing problems.

Tudorza Pressair for other conditions

In addition to the use listed above, Tudorza Pressair may be used off-label. Off-label drug use is when a drug that’s approved for one use is used for a different one that’s not approved. And you may wonder if Tudorza Pressair is used for certain other conditions.

Tudorza Pressair for asthma (not an appropriate use)

Tudorza Pressair should not be used to treat asthma. It’s only FDA-approved to treat COPD in adults. Tudorza Pressair works to open up your airways over time, which can improve COPD symptoms (such as shortness of breath, coughing, or wheezing). It has not been studied as a treatment for asthma.

Tudorza Pressair can interact with several other medications. Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Tudorza Pressair and other medications

Below is a list of medications that can interact with Tudorza Pressair. This list does not contain all drugs that may interact with Tudorza Pressair.

Before taking Tudorza Pressair, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Tudorza and other anticholinergics

Tudorza Pressair should not be used with other drugs that belong to the same drug class, anticholinergics. Taking Tudorza with another anticholinergic may raise your risk for side effects with Tudorza or with the other anticholinergic. It could also make any side effects you get worse.

Examples of other anticholinergic drugs used to treat COPD include:

The above list does not include all anticholinergic medications. Before taking a new medication, check with your doctor or pharmacist to make sure it’s safe to take with Tudorza Pressair.

Tudorza Pressair and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Tudorza Pressair. However, you should still check with your doctor or pharmacist before using any of these products while taking Tudorza Pressair.

Tudorza Pressair and foods

There aren’t any foods that have been specifically reported to interact with Tudorza Pressair. If you have any questions about eating certain foods with this drug, talk with your doctor.

There are no known interactions between Tudorza Pressair and alcohol. If you drink alcohol, talk with your doctor about how much is safe for you to drink while using Tudorza Pressair.

Tudorza Pressair is usually taken with other drugs to treat chronic obstructive pulmonary disease (COPD). The other medications you take will depend on how severe your COPD is and any other medical conditions you may have.

Rescue inhalers

Rescue inhalers contain drugs that work quickly to relax the muscles around your airways. This helps you breathe easier when you’re having trouble breathing. Rescue inhalers are typically used if you’re coughing, short of breath, or if you need to prevent breathing problems while exercising or playing sports.

Examples of rescue inhalers include:

Combination inhalers

Some inhalers contain a combination of a long-acting beta2-agonist (LABA) and another drug, such as a corticosteroid. Both of these types of drugs work to open up your airways over time and are meant to be used on a regular basis.

Examples of combination inhalers include:

* This is an off-label use for this drug. Off-label use is when a drug that’s approved to treat one condition is used to treat a different one.

Inhaled corticosteroids

Inhaled corticosteroids are used on a regular basis to reduce swelling in your airways over time. They can also help relieve symptoms such as coughing and wheezing.

Examples of inhaled corticosteroids include:

  • fluticasone (Flovent HFA, Arnuity Ellipta)*
  • budesonide (Pulmicort)*

* This is an off-label use for this drug. Off-label use is when a drug that’s approved to treat one condition is used to treat a different one.

Oral corticosteroids

If you have moderate or severe COPD symptoms, you may have exacerbations (flare-ups) or worsening of your COPD even when using a rescue inhaler. If that happens, your doctor may also prescribe oral corticosteroids for you.

Oral corticosteroids come as pills that are taken by mouth. They’re typically given for just a few days at a time to help reduce swelling in your airways and improve COPD symptoms.

The most commonly prescribed oral steroid is called prednisone (Deltasone). Prednisone is used off-label to treat COPD. (Off-label use is when a drug that’s approved to treat one condition is used to treat a different one.)

Oxygen therapy

If you have a low oxygen level caused by severe COPD symptoms, your doctor may prescribe oxygen therapy for you. With oxygen therapy, you’ll use a portable oxygen tank that’s connected to a mask or nasal cannula (a tube that sends oxygen into your nose).

Low oxygen levels may happen because COPD makes it more difficult to breathe. This means less air is moving in and out of your lungs. With less air, less oxygen can pass through your lungs and into your blood. Oxygen therapy may be used during certain activities or all day, depending on your needs.

As with all medications, the cost of Tudorza Pressair can vary.

The actual price you’ll pay depends on your insurance plan, your location, and the pharmacy you use.

Your insurance plan may require you to get prior authorization before approving coverage for Tudorza Pressair. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. The insurance company will review the information and let you and your doctor know if your plan will cover Tudorza Pressair.

If you’re not sure if you’ll need to get prior authorization for Tudorza Pressair, contact your insurance company.

Financial assistance

If you need financial support to pay for Tudorza Pressair, help is available. Circassia Pharmaceuticals Inc., the manufacturer of Tudorza Pressair, offers the Tudorza Pressair Savings Guarantee Program. For more information and to find out if you’re eligible for support, call 844-892-7872 or visit the program website.

Tudorza Pressair is used to treat chronic obstructive pulmonary disease (COPD) in adults.

About COPD

COPD is a condition that includes several lung diseases that get worse over time, such as chronic bronchitis and emphysema.

With COPD, your airways become tight and narrow. This makes it harder to breathe. Symptoms of COPD may include cough, shortness of breath, or wheezing. These symptoms usually get worse over time.

What Tudorza Pressair does

Tudorza Pressair contains the active drug aclidinium, which belongs to a class of drugs called anticholinergics.

The active drug in Tudorza Pressair works by attaching to cell receptors (docking stations) in the airways in your lungs and relaxing them. This helps your airways open over time, making it easier to breathe.

How long does it take to work?

Tudorza Pressair starts to work in as little as 10 minutes after you first inhale it. However, it needs to be used twice a day (around 12 hours apart) over time to keep your airways open and improve breathing symptoms.

Tudorza Pressair is not a rescue inhaler, which means it should not be taken when you have sudden difficulty breathing. You should have a different rescue inhaler to help you with sudden coughing or wheezing attacks.

It’s not known whether Tudorza Pressair is safe to use during pregnancy because it hasn’t been studied in pregnant women. Some animal studies have shown that pregnant rats and rabbits who were exposed to Tudorza Pressair in high doses gave birth to offspring with lower than normal weights. However, animal studies don’t always predict what will happen in humans.

It’s unknown whether Tudorza Pressair is safe to take during pregnancy. If you’re sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while you’re using Tudorza Pressair.

Tudorza Pressair has not been studied in breastfeeding mothers, so it’s not known whether it’s safe to use while breastfeeding. Some animal studies have shown that Tudorza Pressair passes into breast milk in rats. However, animal studies don’t always predict what happens in humans.

Talk with your doctor about the risks and benefits of breastfeeding while taking Tudorza Pressair.

Here are answers to some frequently asked questions about Tudorza Pressair.

Is Tudorza Pressair a bronchodilator?

Yes, Tudorza Pressair is a bronchodilator. It contains the active drug aclidinium bromide, which belongs to a class of drugs called anticholinergics. These work by attaching to cell receptors (docking stations) in the airways in your lungs and relaxing them.

Can Tudorza Pressair be used for asthma?

No, Tudorza Pressair cannot be used in people with asthma. It’s not known if it’s safe or effective in people with asthma because there haven’t been studies done to show its effectiveness.

Should I use Tudorza Pressair as a rescue inhaler?

No. Tudorza Pressair is not a rescue inhaler, which means it should not be taken when you have sudden difficulty breathing. You should have a different rescue inhaler to help you with sudden coughing or wheezing attacks.

If I’m allergic to milk, can I still use Tudorza Pressair?

No, you should not use Tudorza Pressair if you have a severe allergy to milk proteins. If you aren’t sure if you have a severe allergy to milk proteins, talk with your doctor about your allergy. They may run some tests to see how severe your allergy is.

Do I need to rinse my mouth after taking a dose of Tudorza Pressair?

No, you don’t need to rinse your mouth after using Tudorza Pressair.

Usually, when people use inhalers that contain a corticosteroid (Qvar, Pulmicort, Flovent HFA, or Asmanex), they need to rinse their mouth out after each dose to prevent a fungal mouth infection called oral thrush. However, Tudorza Pressair contains the active drug aclidinium bromide, which belongs to a class of drugs called anticholinergics. This type of drug does not cause oral thrush.

This drug comes with several precautions. Before taking Tudorza Pressair, talk with your doctor about your health history. Tudorza Pressair may not be right for you if you have certain medical conditions or other factors affecting your health. These include:

  • Glaucoma. If you have a history of glaucoma (increased eye pressure), you may be at higher risk for developing a rare side effect called acute narrow-angle glaucoma when using Tudorza Pressair. If you experience eye pain, blurry vision, or red eyes, or see “halos” or bright colors around lights, call your doctor right away.
  • Urination problems. If you have a history of problems with urination, such as with an enlarged prostate or bladder problems, you may be at higher risk for urinary retention, a rare side effect with Tudorza Pressair. (Urinary retention means not being able to completely empty your bladder.) If you experience difficulty urinating, painful urination, or a drip or weak stream when urinating while taking Tudorza Pressair, call your doctor right away.
  • Severe allergy to milk proteins. If you have a severe allergy to milk proteins, you should not use Tudorza. This is because Tudorza contains some of the same components as milk, and could cause an allergic reaction. If you aren’t sure if you have a severe allergy to milk proteins, talk with your doctor about your allergy. They may run some tests to see how severe your allergy is.
  • Pregnancy. It’s not known if Tudorza Pressair is safe for pregnant women. For more information, see the “Tudorza Pressair and pregnancy” section above.
  • Breastfeeding. It’s unknown if Tudorza Pressair is safe to use while breastfeeding. For more information, see the “Tudorza Pressair and breastfeeding” section above.

Note: For more information about the potential negative effects of Tudorza Pressair, see the “Tudorza side effects” section above.

Do not use more Tudorza Pressair than your doctor recommends.

What to do in case of overdose

If you think you’ve taken too much of this drug, call your doctor. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.

When you get Tudorza Pressair from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. This date is typically 1 year from the date they dispensed the medication.

The expiration date helps guarantee that the medication is effective during this time. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it.

Storage

How long a medication remains good can depend on many factors, including how and where you store the medication.

Tudorza Pressair should be stored at room temperature at 77°F (25°C) in a dry place. It should be kept in the sealed bag until you’re ready to use the inhaler. Dispose of the inhaler after the marking shows “0” with a red background, when the device is empty and locks, or if it’s been 45 days since you opened the sealed bag (whichever comes first).

Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. It should not be stored on a vibrating surface, like a washing machine or dryer.

Disposal

If you no longer need to take Tudorza Pressair and have leftover medication, it’s important to dispose of it safely. This helps prevent others, including children and pets, from taking the drug by accident. It also helps keep the drug from harming the environment.

The FDA website provides several useful tips on medication disposal. You can also ask your pharmacist for information on how to dispose of your medication.

The following information is provided for clinicians and other healthcare professionals.

Indications

Tudorza Pressair is indicated for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults.

Mechanism of action

Tudorza Pressair contains the active drug aclidinium bromide, an anticholinergic agent (also known as an antimuscarinic agent). It works by binding to M3 bronchial smooth muscle receptors, which leads to bronchodilation.

Pharmacokinetics and metabolism

Very little aclidinium is systemically absorbed, with an absolute bioavailability of 6%. Peak steady state plasma levels are achieved 10 minutes after oral inhalation of Tudorza Pressair. It is metabolized and eliminated via esterase hydrolysis, with only 0.09% of the dose eliminated in the urine. Tudorza Pressair has an effective half-life of 5 to 8 hours.

Contraindications

Tudorza Pressair is contraindicated in patients with hypersensitivity to any of the components of the drug formulation. It is also contraindicated in patients with a severe hypersensitivity to milk proteins.

Storage

Tudorza Pressair should be stored at room temperature (77°F/25°C) in a dry place. It should be kept in the sealed bag until it’s going to be used.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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