Phlebothrombosis and thrombophlebitis are both conditions related to blood clots in veins. However, they have distinct characteristics and implications.

Phlebothrombosis refers to a blood clot in a deep vein without significant inflammation. It is also known as deep vein thrombosis (DVT). DVT poses a high risk for pulmonary embolism, which is a blood clot in the lungs.

Thrombophlebitis, on the other hand, involves both a clot and inflammation in a superficial vein. It is typically less severe, but still requires medical attention to manage symptoms and prevent complications.

This article looks at the differences and similarities between the two conditions.

A runner contemplating the difference between phlebothrombosis and thrombophlebitis. -1Share on Pinterest
DavorLovincic/Getty Images
PhlebothrombosisThrombophlebitis
Also known asPhlebothrombosis is also known as deep vein thrombosis (DVT).Thrombophlebitis is also known as superficial vein thrombosis.
LocationThis typically occurs in the deep veins of the legs, located deep within the muscle tissue. It is not visible on the skin’s surface.It usually affects the veins in the legs, but can also present in the arms or neck. The veins will be visible on the surface of the skin.
SymptomsIt may not cause any symptoms initially, or symptoms may be subtle. Symptoms can include swelling, pain, and redness in the affected limb.The affected vein might be visible, red, swollen, and feel warm and tender to the touch.
CausesIt is caused by prolonged periods of inactivity, such as long flights or bed rest. It is also associated with surgery, certain medications, and underlying health conditions.It is associated with vein injury, prolonged inactivity, or after having an intravenous catheter.
Treatment Treatment typically involves anticoagulant medications to prevent further clotting and to reduce the risk of pulmonary embolism.Usually, treatment involves warm compresses, elevation of the affected limb, and nonsteroidal anti-inflammatory drugs (NSAIDs) for pain.
ComplicationsThere is a risk of a blood clot breaking loose and traveling to the lungs. This can cause a potentially life threatening pulmonary embolism.There is a risk of the clot becoming dislodged and causing more serious problems. In rare cases, it can lead to DVT or pulmonary embolism.

Treatments for phlebothrombosis (DVT) include:

  • Anticoagulants: Also known as blood thinners, these medications are the primary treatment for DVT. They prevent new clots from forming and existing clots from getting bigger. Examples include warfarin, heparin, and newer oral anticoagulants such as rivaroxaban or apixaban.
  • Compression stockings: Wearing graduated compression stockings can help reduce the swelling associated with DVT.
  • Elevation and physical activity: Elevating the affected leg and engaging in regular physical activity under the direction of a healthcare professional can help improve blood flow and reduce symptoms.
  • Thrombolytics: In severe cases, doctors might use thrombolytic therapy to dissolve the clot. This is especially true when there is a risk of pulmonary embolism.
  • Surgical intervention: In rare cases, surgical procedures may be necessary. These can include procedures such as thrombectomy, or clot removal.

Treatments for thrombophlebitis (SVT) include:

  • Warm compresses and elevation: Applying warm compresses to the affected area and elevating the limb can reduce discomfort and swelling.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Medications such as ibuprofen can help reduce pain and inflammation.
  • Topical treatments: Topical heparin or similar medications can reduce symptoms.
  • Compression stockings: These can also be beneficial in managing symptoms of SVT.
  • Anticoagulants: In some cases, doctors may recommend short-term use of anticoagulant medications. This is especially true if the patient is at risk for more serious complications.

With prompt diagnosis and proper treatment, many people with DVT recover successfully. The key is to manage the condition to prevent complications.

The most serious risk associated with DVT is pulmonary embolism (PE), which can be life threatening. However, the risk significantly decreases with effective anticoagulant therapy.

Some people may develop post-thrombotic syndrome. This is a condition characterized by chronic pain and swelling. In severe cases, it can cause skin ulcers in the affected limb. This is more likely if the DVT was extensive or if there were delays in treatment.

The prognosis for superficial thrombophlebitis is usually quite good, especially with early treatment. Most cases resolve without serious complications.

With appropriate treatment, symptoms typically improve within a few weeks. This can include NSAIDs, compression therapy, and sometimes topical or systemic anticoagulation.

In some cases, SVT can recur or progress to DVT. Close monitoring and following preventive measures can help reduce this risk.

Thrombophlebitis may also be associated with an underlying condition, such as a clotting disorder or cancer. In these cases, managing the underlying condition is crucial for the overall prognosis.

Read on for answers to some commonly asked questions about thrombophlebitis and phlebothrombosis.

Is thrombophlebitis the same as a blood clot?

In thrombophlebitis, a blood clot forms in a vein, and the vein’s wall becomes inflamed. This distinguishes it from a clot that might occur elsewhere in the body without causing significant vein inflammation.

What is the other name for thrombophlebitis?

Another name for thrombophlebitis is superficial vein thrombosis (SVT). It describes a condition where there is both inflammation of a superficial vein (phlebitis) and the presence of a thrombus (blood clot) within that vein.

The term “superficial” indicates that the affected veins are near the surface of the body. Conversely, deep vein thrombosis (DVT) occurs in the deeper veins.

What are the 3 types of phlebitis?

Phlebitis refers to the inflammation of a vein. It can be classified into three main types based on the location and cause of the inflammation. These are superficial, deep vein, and migratory thrombophlebitis.

Phlebothrombosis and thrombophlebitis are conditions characterized by the formation of blood clots in the veins.

Phlebothrombosis occurs in the deep veins. Without treatment, it can lead to serious complications, such as pulmonary embolism. Thrombophlebitis affects superficial veins and is generally less severe.