Zoryve (roflumilast) is a brand-name topical cream or foam prescribed for plaque psoriasis, atopic dermatitis, and seborrheic dermatitis in adults and some children. The cost of the drug with and without insurance can depend on several factors.

Zoryve cream is approved by the Food and Drug Administration (FDA) to treat atopic dermatitis and plaque psoriasis of the skin and skin folds in adults and children ages 6 years and older.

Zoryve foam is FDA approved to treat seborrheic dermatitis in adults and children ages 9 years and older.

As with all medications, the cost of Zoryve can vary. Factors that may affect the price you’ll pay include:

  • your treatment plan
  • your insurance coverage
  • the pharmacy you use
  • whether Zoryve has a savings program (see the “Financial and insurance assistance” section below)

To find out what the cost of Zoryve will be for you, talk with your doctor, pharmacist, or insurance provider. Or look in the “Zoryve coupons and savings” section to learn how much you can save by using an Optum Perks coupon.

To save money on your Zoryve prescription, explore these Optum Perks coupons.

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Save on Zoryve without insurance.

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Dosage

60gm zoryve (1 Can)

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

Optum Perks and Healthline are subsidiaries of RVO Health.

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Zoryve is only available as a brand-name drug. It does not come in a generic version. A generic drug is an exact copy of the active drug in a brand-name medication.

Generics tend to cost less than brand-name drugs.

WHY ARE COSTS DIFFERENT FOR BRAND-NAME DRUGS VS. GENERIC DRUGS?

Brand-name drugs can be expensive because of the research needed to test their safety and effectiveness. The manufacturer of a brand-name drug can sell it for up to 20 years. When the brand-name drug’s patent expires, multiple manufacturers can create generic versions. This marketplace competition may lead to lower costs for generics. Also, because generics contain the same active ingredients as brand-name drugs, they don’t require the same costly testing.

If you take Zoryve long term, you may be able to lower its cost in the following ways.

Getting a 3-month supply

You may be able to get a 90-day supply of Zoryve. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or insurance provider.

Using a mail-order pharmacy

Zoryve may be available through a mail-order pharmacy. Using this type of service may help lower the drug’s cost and allow you to receive your medication without leaving home. Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.

If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need financial support to pay for Zoryve or help to understand your insurance coverage, help is available. For example:

  • A program called the Zoryve Direct Savings Card is available for Zoryve. For more information and to find out whether you’re eligible for support, visit the program website. You can also enroll using your smartphone: Text SAVE to 440‑4ZORYVE (4​4​0​-​4​9​6​-​7​9​8​3).
  • If you don’t have insurance, you may be eligible for the Arcutis Cares program. For more information, visit the program website or call 855-600-3755.
  • Some websites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Two such websites are:

To learn more about saving money on prescriptions with or without insurance, check out this article.

Here are answers to some frequently asked questions about drug cost and Zoryve.

Is Zoryve covered by Medicare?

It depends. Medicare plans provide coverage for certain prescription drugs. However, there are many plans and they vary by the drugs they cover and other factors. Your coverage and what you pay for prescriptions will depend on your particular plan’s benefits. You can call your Medicare plan provider to learn whether your particular plan covers the cost of Zoryve. (For more information about this, see the “Next steps” section below.)

Keep in mind that you may also need to obtain prior authorization before your plan will cover the cost of Zoryve.

Your doctor or pharmacist may also be able to provide information about your cost for Zoryve if you have Medicare.

What is the cost of Zoryve without insurance?

The price you’ll pay for Zoryve if you don’t have insurance can vary based on several factors. Usually, the cost is higher without insurance. Other factors that could affect what you pay for this drug can include:

  • the quantity you’re prescribed (such as a 90-day or 30-day supply)
  • whether you apply and qualify for any available savings programs
  • the pharmacy you use

To learn the exact cost you’d pay for this medication without insurance, ask your doctor or pharmacist. You may also want to contact several pharmacies to compare their prices for Zoryve.

Check out Optum Perks* for estimates of Zoryve’s price when using coupons from the site. (Optum Perks coupons cannot be used with insurance benefits or copays.)

* Optum Perks is a sister site of Medical News Today.

Below is information you may want to consider if you have insurance and receive a prescription for Zoryve.

If you have insurance, your insurance company may require prior authorization before it covers Zoryve. This means the company and your doctor will discuss Zoryve in regard to your treatment. The insurance company will then determine whether to cover the medication.

If a drug requires prior authorization but you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether Zoryve requires prior authorization.

Now that you’ve learned about cost and Zoryve, you may still have some questions. Talk with your doctor or pharmacist, who can provide personalized guidance about cost issues related to Zoryve. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for Zoryve.

Here are some other resources you may find helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.