Velsipity (etrasimod) is a brand-name drug that’s prescribed for moderate to severe ulcerative colitis in adults. Velsipity comes as a tablet that’s typically taken once per day.

Velsipity belongs to a drug class called sphingosine 1-phosphate receptor modulators. Velsipity is not available in a generic version.

Keep reading for specific information about the dosage of Velsipity, including its strength and how to take the medication. For a comprehensive look at Velsipity, see this article.

Note: This article describes typical dosages for Velsipity provided by the drug’s manufacturer. When taking Velsipity, always follow the dosage prescribed by your doctor.

The information below describes Velsipity’s typical dosage and other details about the drug.

Velsipity form

Velsipity comes as an oral tablet.

Velsipity strength

Velsipity comes in one strength of 2 milligrams (mg).

Typical dosages

The following information describes the dosage that is commonly prescribed. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for ulcerative colitis

Doctors may prescribe Velsipity to treat ulcerative colitis.

If your doctor prescribes Velsipity for your ulcerative colitis, your dose will likely be 2 mg. Typically, you’ll take this once daily. This is the typical recommended dosage of Velsipity for people with ulcerative colitis.

Long-term treatment

Velsipity is meant to be taken as a long-term treatment. If you and your doctor determine that Velsipity is safe and effective for you, you’ll likely take it long term.

Before you start taking Velsipity, your doctor will discuss your treatment plan with you.

Velsipity comes as an oral tablet that you swallow whole. You may take your dose with or without food.

It may be helpful to take Velsipity around the same time of day. This helps maintain a steady level of the drug in your body so Velsipity can work effectively.

If you have trouble swallowing tablets, see this article for tips on how to take this form of medication. You can also talk with your doctor or pharmacist.


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having trouble opening medication bottles, ask your pharmacist about putting Velsipity in an easy-open container. They also may recommend tools that can make it easier to open bottles.

If you miss a dose of Velsipity, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and take your next scheduled dose. Do not take two doses to make up for the missed one. If you’re not sure whether you should take a missed dose or skip it, talk with your doctor or pharmacist.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or putting a note where you’ll see it, such as on your bathroom mirror or bedside table. You could also download a reminder app on your phone.

It’s important that you don’t take more Velsipity than your doctor prescribes. For some medications, taking more than the recommended amount may lead to harmful effects or overdose.

If you take more than the recommended amount of Velsipity

Call your doctor right away if you believe you’ve taken too much Velsipity. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

Below are some frequently asked questions about Velsipity.

How long does it take for Velsipity to start working?

Velsipity starts to work after your first dose because your body absorbs the drug within hours.

In clinical trials, decreases in stool frequency were observed as early as 2 weeks after starting Velsipity, while decreases in rectal bleeding were observed as early as 4 weeks.

Your doctor will monitor you during treatment to check whether the drug is working to treat your condition.

Talk with your doctor if you have questions about what to expect with Velsipity treatment.

Is there a typical dosage range for Velsipity?

Yes, the typical recommended dosage range for Velsipity is 2 mg taken once daily.

For more information about Velsipity dosages, see the “Velsipity dosage” section above. You can also talk with your doctor or pharmacist.

The dosages in this article are typical dosages provided by the drug’s manufacturer. If your doctor recommends Velsipity for you, they will prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes.

As with any drug, never change your dosage of Velsipity without your doctor’s recommendation. If you have questions about the dosage of Velsipity that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Velsipity. These additional articles might be helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.