Tavalisse (fostamatinib) is a brand-name medication that’s prescribed to treat low platelet levels due to chronic immune thrombocytopenia in adults. Tavalisse comes as an oral tablet that’s typically taken twice per day.

Tavalisse belongs to a drug class called kinase inhibitors. Tavalisse is not available in a generic version.

Keep reading for specific information about the dosage of Tavalisse, including its strengths and how to take the medication. For a comprehensive look at Tavalisse, see this article.

Note: This article describes typical dosages for Tavalisse provided by the drug’s manufacturer. When taking Tavalisse, always follow the dosage prescribed by your doctor.

Below is information about Tavalisse’s recommended dosages.

Tavalisse form

Tavalisse comes as an oral tablet.

Tavalisse strengths

Tavalisse comes in two strengths: 100 milligrams (mg) and 150 mg.

Typical dosages

Typically, your doctor will start by prescribing you a low dosage. Then they’ll adjust it over time to reach the amount that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs. In some cases, doctors may adjust your dosage from those shown below.

Dosage for chronic immune thrombocytopenia

Doctors prescribe Tavalisse to treat low platelet levels due to chronic (long-term) immune thrombocytopenia. Tavalisse is typically used when other treatments haven’t worked.

The recommended starting dose of Tavalisse for this use is 100 mg twice daily. After one month, your doctor may recommend increasing your dosage to 150 mg twice daily. This is the maximum dose of Tavalisse that’s recommended.

For more information about your specific dosage, talk with your doctor.

How to take Tavalisse

Tavalisse comes as an oral tablet that you swallow whole. Do not divide, crush, chew, or place the tablet in water. You may take your dose with or without food.

It may be helpful to take Tavalisse around the same time of day. This helps maintain a steady level of the drug in your body so Tavalisse can work effectively.

If you have trouble swallowing tablets, see this article for tips on how to take this form of medication. You can also talk with your doctor or pharmacist.

Long-term treatment

Tavalisse is meant to be taken as a long-term treatment. If you and your doctor determine that Tavalisse is safe and effective for you, you’ll likely take it long term.

Before you start taking Tavalisse, your doctor will discuss your treatment plan with you.


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having trouble opening medication bottles, ask your pharmacist about putting Tavalisse in an easy-open container. They also may recommend tools that can make it easier to open bottles.

It’s important that you don’t take more Tavalisse than your doctor prescribes. For some medications, taking more than the recommended amount may lead to harmful effects or overdose.

Effects of an overdose

Overdose effects of Tavalisse can include:

If you take more than the recommended amount of Tavalisse

Call your doctor right away if you believe you’ve taken too much Tavalisse. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.