Nexlizet (bempedoic acid/ezetimibe) is a brand-name oral tablet prescribed for high cholesterol in adults. The cost of the drug with and without insurance can depend on several factors, such as whether Nexlizet has a savings program.

Specifically, Nexlizet has approval from the Food and Drug Administration (FDA) to treat high cholesterol in adults with:

Nexlizet is approved for use along with statin drugs such as atorvastatin (Lipitor).

As with all medications, the cost of Nexlizet can vary. Factors that may affect the price you’ll pay include:

  • your treatment plan
  • your insurance coverage
  • the pharmacy you use
  • whether Nexlizet has a savings program (see the “Financial and insurance assistance” section below)

To find out what the cost of Nexlizet will be for you, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

To save money on your Nexlizet prescription, explore these coupon options.

Save on your Nexlizet prescription

Save on Nexlizet without insurance.

Enter your information:




180/10mg nexlizet (30 Tablets)

Save money without using insurance

Simply show the Optum Perks coupon at your preferred pharmacy or order online and instantly save up to 80% without using insurance. The coupon doesn't expire so be sure to save it for refills.

Find your pharmacy

Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

Optum Perks and Healthline are subsidiaries of RVO Health.



Was this helpful?

Nexlizet is only available as a brand-name drug. It doesn’t come in a generic version. A generic drug is an exact copy of the active ingredient in a brand-name medication.

Generics tend to cost less than brand-name drugs.


Brand-name drugs can be expensive because of the research needed to test their safety and effectiveness. The manufacturer of a brand-name drug can sell it for up to 20 years. When the brand-name drug’s patent expires, multiple manufacturers can create generic versions. This marketplace competition may lead to lower costs for generics. Also, because generics contain the same active ingredients as brand-name drugs, they don’t require the same costly testing.

If you take Nexlizet long term, you may be able to lower its cost in the following ways.

Getting a 3-month supply

You may be able to get a 90-day supply of Nexlizet. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or insurance provider.

Using a mail-order pharmacy

Nexlizet may be available through a mail-order pharmacy. Using this type of service may help lower the drug’s cost and allow you to receive your medication without leaving home. Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.

If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need financial support to pay for Nexlizet, or if you need help understanding your insurance coverage, support is available. For example:

  • A program called the Nexlizet and Nexletol Copay Card is available. For more information and to find out if you’re eligible for support, call 855-699-8814 or visit the program website.
  • Some sites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Two such websites are:

To learn more about saving money on prescriptions with or without insurance, check out this article.

Here are answers to some frequently asked questions about drug cost and Nexlizet.

How does Nexlizet’s cost compare with that of other similar medications such as Nexletol?

The price you’ll pay for Nexlizet versus that of Nexletol depends on various factors.

Both Nexlizet and Nexletol are oral tablets used to treat high cholesterol. Factors that can affect your prescription cost include:

  • the length of your treatment
  • whether there are payment assistance programs for your prescribed treatment
  • whether you’re paying out of pocket or have insurance

To learn more about the cost of Nexlizet compared with other treatments for your condition, talk with your doctor, pharmacist, or insurance provider.

Is Nexlizet covered by Medicare?

It may be. You can call your Medicare plan provider to learn whether your particular plan covers the cost of this drug. There are many types of Medicare plans, so your coverage and what you pay for prescriptions will be based on your particular plan’s benefits.

Your doctor may also be able to provide information about your cost for Nexlizet if you have Medicare.

How much does Nexlizet cost with insurance vs. without it?

What you pay for Nexlizet if you have insurance compared to what you’d pay without it depends on several factors.

Factors that could affect what you pay for this drug without insurance include:

  • the quantity you’re prescribed (such as a 90-day or 30-day supply)
  • whether you apply and qualify for any available savings programs
  • your dosage and treatment plan
  • the pharmacy you use

These same factors may affect your price for Nexlizet if you have insurance. But the price you pay with insurance will also depend on:

  • your specific plan’s benefits
  • any prior authorization requirements you have for drug coverage

To learn more about what you’d pay for Nexlizet with or without insurance, talk with your doctor, pharmacist, or insurance provider (if you have one).

You can also visit Optum Perks* for price estimates for this drug when using coupons from their site. However, Optum Perks coupons cannot be used with insurance benefits or copays.

* Optum Perks is a sister site of Medical News Today.

Below is information you may want to consider if you have insurance and receive Nexlizet.

If you have insurance, your insurance company may require prior authorization before it covers Nexlizet. This means the company and your doctor will discuss Nexlizet in regard to your treatment. The insurance company will then determine whether the medication is covered.

If a drug requires prior authorization but you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether Nexlizet requires prior authorization.

Now that you’ve learned about cost and Nexlizet, you may still have some questions. Talk with your doctor or pharmacist, who can provide personalized guidance about cost issues related to Nexlizet. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you would pay for Nexlizet.

Here are some other resources you may find helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.