Mydayis (mixed amphetamine salts) is a brand-name drug that’s prescribed for ADHD in adults and some children. Mydayis comes as an oral capsule that’s typically taken once per day.

Mydayis belongs to a drug class called central nervous system (CNS) stimulants. Mydayis is available in a generic version.

Keep reading for specific information about the dosage of Mydayis, including its strengths and how to take the medication. For a comprehensive look at Mydayis, see this article.

Note: This article describes typical dosages for Mydayis provided by the drug’s manufacturer. When taking Mydayis, always follow the dosage prescribed by your doctor.

Below is information about Mydayis’s form, strengths, and dosages.

Mydayis form

Mydayis comes as an extended-release (ER) oral capsule. With ER medications, the drug is slowly released into your body over time.

Mydayis strengths

Mydayis comes in four strengths:

  • 12.5 milligrams (mg)
  • 25 mg
  • 37.5 mg
  • 50 mg

Typical dosages

Typically, your doctor will start by prescribing you a low dosage. Then they’ll adjust it over time to reach the amount that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly prescribed in adults. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for attention deficit hyperactivity disorder

Doctors may prescribe Mydayis to treat attention deficit hyperactivity disorder (ADHD) in adults.

If your doctor prescribes Mydayis for your ADHD, your starting dose will likely be 12.5 mg taken once per day in the morning. After at least one week, your doctor may recommend increasing your dosage by 12.5 mg up to 25 mg. Your doctor may continue increasing your dose by 12.5 mg each week if the medication isn’t working for your condition. The maximum recommended dose of Mydayis in adults is 50 mg once per day.

Children’s dosage

Mydayis is approved to treat ADHD in children ages 13 years and older.

The starting dose is 12.5 mg once per day in the morning. Your child’s doctor can increase their dose after 1 week, to a dose of 25 mg once per day in the morning. The maximum recommended dose of Mydayis in children is 25 mg once per day.

Talk with your child’s doctor if you have questions about their dosage.

Long-term treatment

Mydayis is meant to be taken as a long-term treatment. If you and your doctor determine that Mydayis is safe and effective for you, you’ll likely take it long term.

Before you start taking Mydayis, your doctor will discuss your treatment plan with you.

The Mydayis dosage your doctor prescribes will depend on several factors. These include:

  • your age
  • how your body responds to Mydayis
  • the type and severity of the condition you’re taking Mydayis to treat
  • other medications you take
  • side effects you may have with Mydayis
  • your kidney function

Other medical conditions you have can also affect your Mydayis dosage.

Dosage adjustments

Your doctor may need to adjust your dosage if you take certain medications, such as drugs that affect the pH of your gut or urine. These drugs can affect the level of Mydayis in your body.

Your doctor may also need to adjust your dosage if you have kidney disease.

Be sure to tell your doctor about all medications you take and any health conditions you may have.

Mydayis comes as an oral capsule that you swallow whole. If you or your child cannot swallow the capsule, you can open it and sprinkle it over a spoon of applesauce. Swallow the applesauce right away, without chewing it. Be sure to take your Mydayis dose in the morning, as soon as you wake up.

You may take your dose of Mydayis with or without food. But if you usually take your dose with food, you should always take it with food. And if you usually take your dose on an empty stomach, you should always take it on an empty stomach.

It may be helpful to take Mydayis around the same time each morning. This helps maintain a steady level of the drug in your body so Mydayis can work effectively.

If you have trouble swallowing capsules, see this article for tips on how to take this form of medication. You can also talk with your doctor or pharmacist.

If you have questions about how to take Mydayis, talk with your doctor or pharmacist.


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having trouble opening medication bottles, ask your pharmacist about putting Mydayis in an easy-open container. They also may recommend tools that can make it easier to open bottles.

If you miss a dose of Mydayis, take it as soon as you remember, as long as it’s not later in the day.

If it’s later in the day, your doctor or pharmacist may recommend that you skip the missed dose and take your next scheduled dose the following day. This is because the drug lasts for up to 16 hours in the body. Plus, taking it later in the day may cause insomnia to occur that night. It’s also important that you do not take two doses to make up for a missed one.

If you’re not sure whether you should take a missed dose or skip it, talk with your doctor or pharmacist.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or putting a note where you’ll see it, such as on your bathroom mirror or bedside table. You could also download a reminder app on your phone.

Mydayis has a boxed warning for the risk of misuse and addiction. A boxed warning is the most serious warning from the FDA. It alerts doctors and patients about drug effects that may be dangerous.

Similar to other stimulant medications, Mydayis has the potential for misuse. (Misuse means taking the drug in a way that’s different from how it was prescribed.) Misuse can lead to addiction, which can be serious or even life threatening. (With addiction, a drug is taken even if it’s causing harmful outcomes.)

The use of stimulant medications, such as Mydayis, may lead to heart problems such as heart attack, overdose, seizures, and even death in rare cases. Taking the drug more frequently than prescribed or at higher doses than prescribed increases the risk of these problems. (To learn about Mydayis’s recommended dosages, see the “Mydayis dosage” section above.) Your doctor will monitor you for symptoms of misuse during your treatment with Mydayis.

Before prescribing Mydayis, your doctor will determine whether it’s safe for you to take. If you’ve ever had substance use disorder, your doctor may recommend not taking Mydayis due to the risk of misuse and addiction. In some cases, they may recommend monitoring you more frequently.

Talk with your doctor if you have questions about your risk of misuse with Mydayis.

It’s important that you don’t take more Mydayis than your doctor prescribes. For some medications, taking more than the recommended amount may lead to harmful effects or overdose.

Symptoms of an overdose

Overdose symptoms of Mydayis can include:

If you take more than the recommended amount of Mydayis

Call your doctor right away if you believe you’ve taken too much Mydayis. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

Treatment with Mydayis can cause dependence. With dependence, your body becomes used to a drug and needs it to function as usual. This means you may have withdrawal symptoms if you suddenly stop taking Mydayis after taking it regularly for some time. (Withdrawal symptoms are side effects that happen after you stop taking a drug your body has become dependent on.)

Symptoms of withdrawal after abruptly stopping Mydayis include:

These symptoms can be very uncomfortable. However, they’re usually not life threatening.

You and your doctor will periodically reevaluate your need for Mydayis throughout your treatment. If a decision is made to stop your Mydayis treatment, your doctor will slowly lower your dose over time. This is known as a dose taper. A dose taper helps reduce your risk of withdrawal symptoms when you stop treatment with Mydayis.

Tapering your Mydayis dose could last several weeks or even months. The exact time needed to taper your dose depends on your Mydayis dose and how long you’ve taken it.

Do not stop taking Mydayis unless your doctor specifically tells you to do so. If you have questions about your treatment, talk with your doctor.

Below are some frequently asked questions about Mydayis.

Is the dosage of Mydayis similar to the dosage of Adderall or Vyvanse?

Yes, the forms and how often you take each drug are similar. Mydayis and Vyvanse are both oral capsules that are taken once daily. Both of these medications are extended-release forms, which work slowly over time. Adderall is available as an extended-release oral capsule and as an immediate-release oral tablet.

The dose in milligrams for each drug differs. Your doctor will prescribe the drug and the dosage that’s right for you.

To learn more about how these drugs compare, talk with your doctor.

What is the recommended maximum dosage of Mydayis?

The maximum dosage of Mydayis that’s recommended for adults is 50 mg once per day in the morning.

Typically, doctors prescribe a lower dosage to start. In some cases, doctors may increase the drug’s dosage. The highest dose of Mydayis recommended per day is 50 mg. No additional benefits are seen with doses higher than 50 mg. For details about Mydayis dosages, see the “Mydayis dosage” section above.

If you have questions or concerns about your dosage of Mydayis, talk with your doctor or pharmacist. If it seems like you need a higher dosage, ask your doctor whether a dosage increase is right for you. Do not increase your dosage unless your doctor recommends doing so.

The dosages in this article are typical dosages provided by the drug’s manufacturer. If your doctor recommends Mydayis for you, they will prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes.

As with any drug, never change your dosage of Mydayis without your doctor’s recommendation. If you have questions about the dosage of Mydayis that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Mydayis. These additional articles might be helpful:

  • More about Mydayis: For information about other aspects of Mydayis, refer to this article.
  • Drug comparison: To find out how Mydayis compares with Adderall, read this article.
  • Details about ADHD: For details about ADHD, see our ADHD hub.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.