Eysuvis (loteprednol) is a brand-name drug that’s prescribed short term to treat symptoms of dry eye disease in adults. Eysuvis comes as an eye drop that’s typically applied four times per day.

Eysuvis belongs to a drug class called corticosteroids. Eysuvis is not available in a generic version.

Keep reading for specific information about the dosages of Eysuvis, including its strength and how to apply the medication. For a comprehensive look at Eysuvis, see this article.

Note: This article describes the typical dosages for Eysuvis provided by the drug’s manufacturer. When applying Eysuvis, always follow the dosage prescribed by your doctor.

The information below describes Eysuvis’s typical dosages and other details about the drug.

Eysuvis form

Eysuvis comes as a liquid suspension eye drop.

Eysuvis strength

Eysuvis comes in one strength of 0.25%. Each bottle contains 8.3 milliliters (mL) of medication.

Typical dosages

The following information describes the dosages that are commonly prescribed or recommended for adults. However, be sure to follow the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosages for dry eye

Doctors may prescribe Eysuvis to treat dry eye disease. The recommended dosage of Eysuvis is one to two drops in each eye four times per day.

For more information about your specific dosage, talk with your doctor.

Short-term treatment

Eysuvis is prescribed short term for treating the signs and symptoms of dry eye disease. It’s prescribed for up to 2 weeks when you’re experiencing symptoms of dry eye disease, also known as a dry eye flare. Eysuvis isn’t a long-term treatment for dry eye disease.

Talk with your doctor if you have questions about how long you can expect treatment with Eysuvis to last.

The Eysuvis dosage your doctor prescribes will depend on several factors. These include:

  • how your body responds to Eysuvis
  • the type and severity of the condition you’re prescribed Eysuvis to treat
  • side effects you may have from Eysuvis

Other medical conditions you have can also affect your Eysuvis dosage.

Eysuvis comes as a liquid suspension eye drop. It is recommended to wash your hands before applying Eysuvis. If you wear contact lenses, you’ll take them out before applying the eye drops. You can put them back in 15 minutes after applying Eysuvis.

To apply Eysuvis, shake the bottle gently for 2–3 seconds. Tilt your head back and hold the bottle above your eye. Squeeze the bottle gently to put one or two drops in each eye.

Be careful not to touch the tip of the dropper to your eye or any other surface, as this could contaminate the eye drops. This could lead to an eye infection.

If you have questions about how to apply Eysuvis, talk with your doctor or pharmacist. There are also instructions available on the manufacturer’s website.


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you miss a dose of Eysuvis, apply it as soon as you remember. If you’re not sure whether you should apply a missed dose or skip it, talk with your doctor or pharmacist.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or putting a note where you’ll see it, such as on your bathroom mirror or bedside table. You could also download a reminder app on your phone.

It’s important that you do not apply more Eysuvis than your doctor prescribes. For some medications, applying more than the recommended amount may lead to harmful effects or overdose.

If you apply more than the recommended amount of Eysuvis

Call your doctor right away if you believe you’ve applied too much Eysuvis. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number or go to the nearest emergency room.

Below are some frequently asked questions about Eysuvis.

How long does it take for Eysuvis to start working?

Eysuvis starts to work after your first dose. Some people may notice their dry eye symptoms, such as eye discomfort, easing by the fourth day of treatment. However, it may take up to 14 days to experience the full effect of the drug, including a reduction in eye redness.

Talk with your doctor if you have questions about what to expect with Eysuvis treatment.

Is there a typical dosage range for Eysuvis?

Yes, the typical recommended dosage range for Eysuvis is one or two drops in each eye four times per day for up to 2 weeks.

In some cases, doctors may start at the lower dosage and increase it if needed. The goal is to find the lowest dose that’s effective for you. This helps reduce your risk of side effects from the drug.

For more information about Eysuvis dosages, see the “Eysuvis dosage” section above. You can also talk with your doctor or pharmacist.

The dosages in this article are typical dosages provided by the drug’s manufacturer. If your doctor recommends Eysuvis for you, they will prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes.

As with any drug, never change your dosage of Eysuvis without your doctor’s recommendation. If you have questions about the dosage of Eysuvis that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Eysuvis. These additional articles might be helpful:

  • More about Eysuvis. For information about other aspects of Eysuvis, refer to this article.
  • Side effects. To learn about side effects of Eysuvis, see this article. You can also look at the Eysuvis prescribing information.
  • Details about dry eye disease. For details about dry eye disease, see our eye health hub.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.