Evamist (estradiol) is a brand-name drug that’s prescribed for adults to treat hot flashes caused by menopause. It comes as a spray that you apply to your skin. The cost of the drug can depend on several factors, such as your insurance coverage.

As with all medications, the cost of Evamist spray can vary. Factors that may affect the price you’ll pay include:

  • your treatment plan
  • your insurance coverage
  • the pharmacy you use
  • whether Evamist has a savings program or coupon (see the “Financial and insurance assistance” section below)

To find out what the cost of Evamist will be for you, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

To save money on your Evamist prescription, explore these Optum Perks coupons for various forms of the drug.

Save on your Evamist prescription

Save on Evamist without insurance.

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1mg estradiol (30 Tablets)

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Simply show the Optum Perks coupon at your preferred pharmacy or order online and instantly save up to 80% without using insurance. The coupon doesn’t expire, so be sure to save it for refills.

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

Optum Perks and Healthline are subsidiaries of RVO Health.

Pricing source:Perks.optum.com

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Evamist is only available as a brand-name drug. It doesn’t come in a generic version. A generic drug is an exact copy of the active ingredient in a brand-name medication.

Generics tend to cost less than brand-name drugs.

Note: Estradiol, the active ingredient in Evamist, does come as a generic in other forms such as creams and patches. But it doesn’t come as a spray, which is the form of Evamist. If you’d like to know more about other forms of estradiol, talk with your doctor.

WHY ARE COSTS DIFFERENT FOR BRAND-NAME DRUGS VS. GENERIC DRUGS?

Brand-name drugs can be expensive because of the research needed to test their safety and effectiveness. The manufacturer of a brand-name drug can sell it for up to 20 years. When the brand-name drug’s patent expires, multiple manufacturers can create generic versions. This marketplace competition may lead to lower costs for generics. Also, because generics contain the same active ingredients as brand-name drugs, they don’t require the same costly testing.

If you take Evamist long term, you may be able to lower its cost in the following ways.

Getting a 3-month supply

You may be able to get a 90-day supply of Evamist. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or insurance provider.

Using a mail-order pharmacy

Evamist may be available through a mail-order pharmacy. Using this type of service may help lower the drug’s cost and allow you to receive your medication without leaving home. Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.

If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need financial support to pay for Evamist, or if you need help understanding your insurance coverage, help is available. For example:

  • A manufacturer’s coupon is available for Evamist. For more information and to find out whether you’re eligible for support, call 1-844-415-0672 or visit the program website.
  • Some websites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Two such websites are:

To learn more about saving money on prescriptions with or without insurance, check out this article.

Here are answers to some frequently asked questions about drug cost and Evamist.

What’s the cost of Evamist without insurance?

If you have insurance, your cost for Evamist spray depends on factors such as:

  • your particular plan benefits, including your drug copay amount
  • your dosage of the drug
  • whether you apply and qualify for their cost coupon

To find out how much Evamist will cost you with insurance, contact your insurance provider or doctor.

You can also visit Optum Perks* for price estimates for Evamist spray when using coupons from the site. However, Optum Perks coupons cannot be used with any insurance benefits or copays.

* Optum Perks is a sister site of Medical News Today.

Is Evamist covered by Medicare?

It may be. You can call your Medicare plan provider to learn whether your particular plan covers the cost of this drug. There are many types of Medicare plans, so your coverage and what you pay for prescriptions will be based on your particular plan’s benefits.

You may also need to obtain prior authorization before your plan will cover the cost of this medication.

Your doctor may also be able to provide information about your cost for Evamist if you have Medicare.

If you have insurance, your insurance company may require prior authorization before it covers Evamist. This means the company and your doctor will discuss Evamist in regard to your treatment. The insurance company will then determine whether the medication is covered.

If a drug requires prior authorization but you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether Evamist requires prior authorization.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.