Camzyos (mavacamten) is a brand-name oral capsule that’s prescribed for obstructive hypertrophic cardiomyopathy with symptoms in certain adults. Camzyos is typically taken once per day. The dosage can vary depending on certain factors.

Camzyos is approved by the Food and Drug Administration (FDA) to treat obstructive hypertrophic cardiomyopathy (HCM) that:

  • has symptoms
  • meets certain criteria relating to symptom severity

Camzyos belongs to a drug class called cardiac myosin inhibitors (blockers). This means Camzyos’ mechanism of action (how it works) is by blocking the protein cardiac myosin. Camzyos is not available in a generic version.

Keep reading for specific information about the dosage of Camzyos, including its strengths and how to take the medication. For a comprehensive look at Camzyos, see this article.

Note: This article describes typical dosages for Camzyos provided by the drug’s manufacturer. When taking Camzyos, always follow the dosage prescribed by your doctor.

Below is information about Camzyos’ form, strengths, and dosages.

Camzyos form

Camzyos comes as an oral capsule.

Camzyos strengths

Camzyos comes in four strengths:

  • 2.5 milligrams (mg)
  • 5 mg
  • 10 mg
  • 15 mg

Typical dosages

Typically, your doctor will start by prescribing you a low dosage. Then, they’ll adjust it over time to reach the amount that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly prescribed or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs. In some cases, doctors may adjust your dosage from those shown below.

Dosage for obstructive hypertrophic cardiomyopathy

Doctors may use Camzyos to treat obstructive HCM. The usual starting dose is 5 mg once per day. After 4 weeks, your doctor will do a checkup and order an echocardiogram (testing for your heart). Then, they may keep the same dosage or lower your dose to 2.5 mg once per day.

Your doctor will monitor you often during treatment. Based on their findings, they’ll adjust, pause, stop, or continue the treatment. There’s no typical Camzyos dosage for people with obstructive HCM. The dosing is individualized based on checkups and echocardiogram results. The maximum recommended dose is 15 mg once per day.

For more information about your specific dosage, talk with your doctor.

How to take Camzyos

Camzyos is an oral capsule that you swallow whole. Don’t crush, chew, or open it. If you have difficulty swallowing capsules, see this article for tips or consult a pharmacist. Take Camzyos exactly as prescribed by your doctor. Typically, you’ll take it once per day, with or without food.

With Camzyos, it’s important to tell your doctor about all of the drugs, over-the-counter products, and supplements you take. Some may interact with Camzyos and affect its activity. Camzyos drug interactions may lead to side effects or harmful effects.

Inform your doctor right away of side effects, including swelling, chest pain, breathlessness, weight gain, racing heart, or fatigue. They may alter, pause, or stop treatment if certain Camzyos side effects occur. Follow their guidance for any changes. Don’t alter the dose or how you take it without your doctor’s advice.

Taking Camzyos may reduce your obstructive HCM symptoms and help you be more active. However, due to its risks, you’ll still need monitoring for safety. You’ll need regular checkups and echocardiograms. Try to keep these appointments. This will help your doctor in managing your condition, symptoms, and treatment.

If you have questions about how to use Camzyos, talk with your doctor or pharmacist. There are also instructions and a medication guide on the manufacturer’s website. Be sure to read the medication guide before taking Camzyos.

Long-term treatment

Camzyos is meant to be taken as a long-term treatment. If you and your doctor determine that Camzyos is safe and effective for you, you’ll likely take it long term.

Talk with your doctor if you have questions about how long you can expect to take Camzyos.


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having difficulty opening medication bottles, ask your pharmacist about putting Camzyos in an easy-open container. They also may recommend tools that can make it easier to open bottles.

It’s important that you don’t take more Camzyos than your doctor prescribes. Taking more than the recommended amount may lead to harmful effects or overdose. A Camzyos overdose can be dangerous and life-threatening.

Effects of an overdose

Overdose effects of Camzyos can include:

If you take more than the recommended amount of Camzyos

Call your doctor right away if you believe you’ve taken too much Camzyos. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.